diff --git a/package/libiio/libiio.mk b/package/libiio/libiio.mk
index aec251e9a1..b36ea3bafe 100644
--- a/package/libiio/libiio.mk
+++ b/package/libiio/libiio.mk
@@ -13,8 +13,6 @@ LIBIIO_LICENSE_FILES = COPYING.txt
 LIBIIO_CONF_OPTS = -DENABLE_IPV6=ON \
 	-DWITH_LOCAL_BACKEND=$(if $(BR2_PACKAGE_LIBIIO_LOCAL_BACKEND),ON,OFF) \
 	-DWITH_NETWORK_BACKEND=$(if $(BR2_PACKAGE_LIBIIO_NETWORK_BACKEND),ON,OFF) \
-	-DWITH_MATLAB_BINDINGS_API=OFF \
-	-DMATLAB_BINDINGS=OFF \
 	-DINSTALL_UDEV_RULE=$(if $(BR2_PACKAGE_HAS_UDEV),ON,OFF) \
 	-DWITH_TESTS=$(if $(BR2_PACKAGE_LIBIIO_TESTS),ON,OFF) \
 	-DWITH_DOC=OFF